Silent spreaders’: Evidence grows that children may play a larger role in transmission than once believed2 pediatric patients seen at Boston’s Massachusetts General Hospital and Mass General Hos 2800w
Silent spreaders’: Evidence grows that children may play a larger role in transmission than once believed2 pediatric patients seen at Boston’s Massachusetts General Hospital and Mass General Hos 2800w
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Silent spreaders’: Evidence grows that children may play a larger role in transmission than once believed
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2 pediatric patients seen at Boston’s Massachusetts General Hospital and Mass General Hospital for Children, 49 were diagnosed with acute infection and another 18 with MIS-C, the multi-inflammatory syndrome linked to the virus. The mean age of the children in the study was 10 years. The percentage of children who tested positive for the virus was about 25 percent, Fasano said, as compared with about 20 percent for adults.
Among the other preliminary findings: Age did not impact viral load (or amount of virus present) and that viral load appeared especially high about two days into the infection.
Another eye-opening finding involves immune receptors known as ACE2 that the virus uses to invade the body. Scientists had hypothesized that because children may have lower numbers of the receptors, they may be less likely to be infected or to transmit the virus. The data confirmed that younger children do have lower numbers of receptors than older children and adults — but that this did not seem to be related to viral load.