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& (140.0mmHg), (15 (2006) (2006), (2007) (2007), (2007: (2008), (2009) (2009), (2010), (2011) (2011), (2012) (2012), (2012: (2013) (2013), (2014), (2015), (2016) (2016), (2017) (2017), (2018) (2018), (2018: (2019) (2019), (2nd (3.3 (3.8mmHg (3rd (4th (5th (7th (8th (90.3±11.47 (90mmHg). (95% (Acupuncture (BMI) (BNI), (Bettany-Saltikov, (Bolivar (Bradley, (Bronsert (Burns (C) (CASP) (CASP, (CINAHL), (Cevik (Chang (Chang, (Charles (Chen (Chen, (Chines (Clarke, (Coughlan (Courtney (DARTNet) (Dieterle (EMBASE), (Eds.), (Emparanza (Ettehad (Excluding (Fang (Flachskampf (Gray (Grove (Habacher (Holland (Houser, (I) (Jackson (Kawakita (Keele, (Kim (Lee (Li (Lin (Litscher (LoBiondo-Wood (MEDLINE) (Macklin (Macnee (McDonald, (Moher (Moule (NICE) (NICE, (National (Nelson (O) (Oxford (P) (PICO) (Polit (RAAS) (RCT) (SHARP): (Schneider (TCM) (Tappen, (Titler (UK), (Wang (Webb (Wu (Xiang (Yang (Yin (Zhang (Zheng (a) (b) (diastolic) (diastolic), (e.g. (excluding (if (including (modern (n (n=1) (n=1). (n=1, (n=2, (n=3), (n=3, (n=4), (n=4, (n=5, (no (not (online), (overall (p.1149) (p.3) (p.3122) (p.3124) (p.415) (p.840) (p.842); (p.919) (p<0.001). (p<0.01). (p=0.006). (p=0.041). (p=0.16). (p>0.68). (specified) (specified), (systolic) (systolic, (the (though (where -2.81 -3.56 -3.6 -3.84 -4.0 -4.32 / 0) 0.0+1 0.01 0.1 0.2 0.6 1 1, 1-15. 1-2, 1. 1.0 1.1 1.2 1.3 1.31 1.5 1.6 10 10, 102 102) 1059-1065. 10mmHg 11 11, 115, 119, 12 12-month 12.5 122-128. 122.1/76.8 122.1/76.8mmHg, 13.6mmHg 131.0mmHg 136.8/83.7 136.8/83.7mmHg 14-20. 140-159 140.6mmHg 140.6mmHg, 140/90 147 149.6mmHg 15 15) 15, 15-16. 15.2%). 16 16-18. 16.0%) 16.7%) 160 169, 17 17.3mmHg 179/109 18 18, 185-194. 19 19.3 192 1: 2 2. 2.0 2.1 2.2 2.3 2.4 2.5 2.5mmHg 2.6 2.7 20 20, 20.0% 2004 2005 2006 2006), 2006). 2006: 2006; 2007 2007) 2007), 2007). 2007: 2007; 2008). 2008: 2009) 2009), 2009). 2009); 2009, 2009; 2010). 2010; 2011), 2011). 2012 2012) 2012), 2012). 2012); 2012: 2012; 2013), 2013). 2013; 2014) 2014). 2014; 2015), 2015). 2015; 2016 2016) 2016). 2016: 2016; 2016]). 2017). 2017, 2017: 2018 2018) 2018), 2018). 2018); 2019 2019) 2019). 2019, 2019: 21 21, 22 22, 227-233. 23, 237-254. 24, 25, 2500 26, 27/160 28 280-285. 287-295. 29, 2: 3 3, 3. 3.0 3.1 3.1.1 3.1.2 3.1.3 3.2 3.2.1 3.2.2 3.2.3 3.2.4 3.2.5 3.3 3.3.1 3.3.2 3.3.3 3.3mmHg, 3.5 3.6mmHg) 3.7 3.7mmHg 30 30, 30.0% 3121-3129. 317-326. 32 32, 33 33.3%) 34, 35, 38, 387, 3: 4 4, 4.0 4.1 4.2 4.3 4.4 4.5 4.6 40 41 412-420. 42 42-45. 428 45, 453-461. 462-466. 48, 480-488. 4: 5 5, 5. 5.0 5.2mmHg 5.8) 5/33 50.0%) 50.0%), 506-514. 51, 529-538. 57-58. 5: 6 6) 6, 6-month 6. 6.3, 6.4 6.4mmHg 658-665. 66.7%) 6: 7, 7. 7.0mmHg. 73-76. 7: 8 8, 8. 81.0mmHg 83-94. 83.3%) 83.3%), 838-845. 87 87) 87.8±9.16 88.9 88.9mmHg, 8: 9 9) 9, 9.2); 90-99 918-923. 94.1mmHg 95% 95.0% 957-967. 96, 98-103. <50 <http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/> <https://casp-uk.net/wp-content/uploads/2018/01/CASP-Randomised-Controlled-Trial-Checklist-2018.pdf> <https://ebn.bmj.com/content/14/3/64.citation-tools> <https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140825> <https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008821.pub2/epdf/full> <https://www.gov.uk/government/publications/health-matters-combating-high-blood-pressure/health-matters-combating-high-blood-pressure> <https://www.hindawi.com/journals/ecam/2012/875284/> <https://www.hindawi.com/journals/ecam/2013/808971/> <https://www.hindawi.com/journals/ecam/2013/956967/> <https://www.hindawi.com/journals/ecam/2014/279478/> <https://www.hindawi.com/journals/ecam/2016/6908710/> <https://www.hindawi.com/journals/ecam/2018/1638904/> <https://www.hindawi.com/journals/ijhy/2019/8676490/> <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684577/> <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205676/> <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872229/> <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996195/> <https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26632749/> <https://www.ncbi.nlm.nih.gov/pubmed/19621072> <https://www.nice.org.uk/guidance/cg127/resources/hypertension-in-adults-diagnosis-and-management-pdf-35109454941637> <https://www.nmc.org.uk/globalassets/sitedocuments/nmc-publications/nmc-code.pdf> = =102) A A, AB, AE, AJ AL, AND AR, AT, Abstract Accessed Across Action, Active Acupoint/s Acupuncture Acupuncture, Additional Administration, Adults: Advanced Again, Ai, Aim Aims: All Allied Alternative Although Altman, American An Anaesthesia Analysis Anderson, Angeles: Another Anti-Hypertensive Anti-hypertensive Antihypertensive Any Appendices Appendix Appraisal Appraisal, Appraising Appropriateness Are As Aside Assessment At Australia. Average Aveyard Aveyard, B BE BFL, BG, BMI BMJ BP BP, BP. BP: BY, Back-chaining Background Background: Bai, Balneaves, Bartlett Based Because Beck, Behaviour Bellamy, Berkshire: Bettany-Saltikov, Biopsychosocial Black Black, Blackwell Blinding Blood Board Bolivar, Boolean Bradley, British Broader Bronsert, Brown, Buckley, Buczynski, Building Burls, Burns, C C, CA, CASP CC CH, CI CI, CINAHL CL CN CP CS, CT CX CY, Cabello, Callender, Can Cao, Cardiology, Care Care, Care: Centre Cevik Cevik, Chai, Chalmers, Chang, Change Chapter Characteristics Charles, Chatswood: Chen Chen, Chengdu China Chinese Cho, Choi, Chou, Choue, Circulation, Clarke, Clinical Cochrane Code Code: Collaboration Combating Company. Comparative Comparator Comparator/s Complementary Comprehensive Conclusion Conclusions: Conducted Confounding Contents Context Continuing Control Controlled Coughlan, Council Council’s Courtney, Creating Criteria Critical Cronin, Cui, Cumulative D D, DF DG DZ, Dai, Daniel, Data Database Databases Definition Detailed Diagnosis Diagnostic Diagram Did Dieterle, Discovering Discussion Disparities Dissertation Do Dobbs, Does Doing Dong, Du, Dumville, Duplicates) E EA, EG EMBASE ETC Each Edn.), Education Education. Edwards, Effective Effectiveness Effects Efficacy Electronic Electrotherapy Eligibility Elsevier Elsevier. Elsevier/Saunders. Emberson, Emdin, Emparanza, England English English-language English. Ernst, Essential Essentials Ettehad, Evaluation Evidence Evidence-Based Evidence-based Excellence Excerpta Exclusion Experimental Extraction F FA, FR Family Fang, Fengchi Final Finally, Finding Finding/s Findings Findings: Firstly, Five Flachskampf Flachskampf, Follow-up For Foreman, Free From Full-text Further Further, Future G G, GJ, GS, Gallasch, Gan, Garossino, Gefeller, General Generation German Germany Gerrish, Goertz, Goodman, Gray, Green Green, Groups Grove Grove, Guide Guide, Gynaecology, H H, HJ HJ, HK, HM, HR HR, HY, Ha, Habacher, Haber, Half Hammermeister, Handbook He, Health Healthcare Heights: Help Henderson, Hg Hg, Hg; Higgins Higgins, High Hill Hill/Open Holland, Hooper-Lane, Hosokawa, Houser Houser, How However, Hu, Huang, Hypertension Hypertension, Hypothalamus-related IS IS, Identification If Improvement, In Included Inclusion Inclusion/Exclusion Increasingly, Indeed, Index Innovative Institute Internal International Intervention Interventions, Introduction, Iseri Iseri, It J J, J,Guo, JB JE, JG, JH JI, JJ JK JM, JN JR, JWF, JY Jackson, Jin, Jones Journal July Jung, K K, KH KM, KO KY, Kalish, Kawakita Kawakita, Keele, Keywords Kim Kim, Kingdom Kiran, Klinghammer, Kluwer Ko, Koh, Korea Korean Korean) Korean). L L, LA, LG, LR3) Lam, Lan, Lancet, Lao, Laser Lathlean, Law Law, Learning. Lectures Lee, Levels Lewis’ Li Li, Liang, Liberati, Limitations Limiters Lin, Lippincott Literature Litscher, Liu Liu, LoBiondo-Wood, Location London: Longitudinal Los Louis: Ltd. M M, MA MAY MC MCM, MD MEDLINE/PUBMED MG MH MR, Ma, Macklin Macklin, Macnee, Make Management Management, Management: Mao, March Maryland Masters Mateo, Matters: McCabe, McCutcheon, McDonald McDonald, McGraw Mean Measured Mechanism Medica Medical Medical-Surgical Medication/s Medicine Medicine, Meridian Merit Meta-analysis Methodology Methods Methods: Miao, Midwies, Midwifery Missouri: Moher, Moon, Morris, Mosby-Elsevier, Mosby. Most Moule, Moxibustion, Multiple N N, N=1: N=3: N=4: NJ NOT NY, National Needle Negative Nelson, Neurological Nevertheless, New Ng, Ning, No None Not Number Nurses Nurses: Nurse’s Nursing Nursing, Nursing: O, OR OR. Observation Obseterics Okada, One Online Only Open Other Others Otherwise, Ou, Outcome Overall, Overview Oxford Oxford: P P, P=0.90; PF PICO PLOS PLoS PM, PRISMA Pain Pain, Park, Part Participants Patients Period Perspectives Pfahlberg, Pflederer, Philadelphia: Physician, Pian-Smith, Pittler, Placebo Polit, Population Practical Practice Practice, Practice: Precise: Preferred Press. Press/McGraw Pressure, Prevalence, Prineas, Problems Process Professional Programme Promoting Protocols Public Publications. Published Publishing Publishing, Puyat, Q Q, Qian, Qu, Qualitative Quality Quantitative Question Questions R R, RAAS RCT RE RH, RJ, RM Rahimi, Randomised Rationale Reading Reading, Recommendations Records Reducing Rees, Reference References Related Ren, Reports, Research Research, Research: Resources Results Review Reviewing Reviews Reviews, Rodgers, Roe Roe, Role Ryan, S S, S1, SAGE SAGE. SG, SK SK, SM SO SU, SY, Saam Sang, Saunders. Schneider, Science Science. Screening Search Searches Searching: Seaton, Secondary Secure See Selected Selection Selections Sense Seo, Sham Shanghai Shen Shen, Shi, Shin, Significantly, Similarly, Skills Skills. Social Sohn, Some South Spanish Springer St Standards States Step-By-Step Steps Stevens, Stop Studies Studies, Study Subsequently, Success, Sudbury: Summary Sun, Sussex, Sustainability Sydney: Synthesis Systematic Systolic T T, TCM TOTAL TP Taiwanese Tan, Tang, Tappen, Ten Terms Tested Tetzlaff, The Theory Therapies Therapy, There Therefore, These They This Thompson,J, Three Thus, Tian, Titler, To Torgerson, Traditional Treatment/s Trial Trial, Trials Triscott, Turbulence Two Two-thirds Type Type/s Types U UK UK, UK: USA Uncertain Undergraduate Understanding United University Up Use Using Valaskatgis, Valuck, Vasodilation Veterinary Visual W W, WG WG, WL, WS, WY, Wald, Wang Wang, Was Wayne, Web Webb Webb, Wei, Were West Western What When Where Whitehead, Why Wiley-Blackwell, Wiley. Wilkins. Williams Wolters Wortmann, Wright,JM Wu, X X, XG, XM XM, XR, XY, Xiang, Xie, Xiong, Xu, Xue, Y Y, YC YH YJ, YL, YM YN, YT, Yang Yang, Ye, Yes Yes, Yeung, Yin Yin, Ying, Yoo, York: You You, Yu, Z Z, ZHENG Zhai, Zhang Zhang, Zhao Zhao, Zheng Zheng, Zhou, Ziea, Zusman, [Flachskampf [NICE], a about above. abstract abstract, academic acceptable access accessed, accessing according accounted accurate, accurately achieved achieving across action active activity activity, activity. actual actually acupoint acupoints acupoints, acupoints. acupuncture acupuncture, acupuncture. acupuncture: acupuncture; acupuncture?, acupuncture’s adding addition additional address address. addressed, adjunctive adjusted administer administered administering adult* adults adults, advanced adverse affect affected. affecting affects after again age age, agree agreed aim aims al. al., al.’s all all-cause allocated alone along also alternative although always ambulatory among amplified an analyse analysed analyses analysis analysis, and and, and/or animals annum annum. another answer answerable answering ant-hypertensive anti-hypertensive anti-hypertensives antihypertensive any any) apples application applied apply appraisal appraisal. appraisals appraise, appraised. approach approach, approach. approaches approaches, appropriate appropriately approximated are are, argued arise. around arterial articles as asked aspects assessed assessing assessor-blinded assignment associated assume asterisk; at atherosclerotic attempt authors available available, average averaged. avoid aware back based based. baseline basic basis be because because, become been began begins being belief believed benefit benefits bespoke best best. between beyond bias biased billion bleeding blinding blinding. block blockages blood body body’s both brain broad broader but by calculated came can capture captured cardiovascular cardiovascular-related care carefully case cases cases, cause cause, caused causes causes, caution cerebellum, certainly change change, change. changed changes characteristics choose chose chronic chronically circadian citation, cited claim classes classes: classification clear clear, clearly-focused clinical clinically-important clinician clinicians clinicians, cohort cohort. cohorts cohorts. combination combination, combined commencement commitment common community-dwelling company. comparative comparator compared comparison completed completed, completed. complex. complexities complicated complicating comprehensiveness conclude concluded concludes conclusion conclusion? conclusions condition. conditions conducted conference confidence confirmed confounder confounder. confounders confounding confounding. connectivity consensus consider consider. consideration consideration. considerations considered considered, considered. considered? considering considers consistently consumption containing context context? continue continuous continuous/ongoing control controlled controlled, controlling controls convenience correlated costs costs? could created creating criteria critical critically criticised cumulative cupping current current, data database databases databases. date date, death: decade decrease decreased decreases definition delivered, delivers demographic depending depth design designed despite detail detailed determine determining develop developed developed: developing development device devices diagnosed diagnoses diagnosing diagnosis diagnostic diagram diastolic did did, diet, dietary differ difference: differences different difficult difficulties diluted diminish directions, directly discusses discussion disease disease. disease: disorder disordered disordered, disorders, disparities disparity dissertation distributed divided do done dose double-blind, drawing drugs drugs, due duplicates duplicates). duration duration. during each earlier earlier. easily educating education effect effect. effect; effect? effective effective, effective. effectiveness effects efficient either electrical electro-acupuncture electro-acupuncture, electronic eligibility eliminated emphasise emphasised enable endings energy, enrolled ensure ensured entered entire environmental epidemiological epigenetic equally equally? essential estimate estimates et etc. etc.) ethnicity, etiology even event events events, every evidence evidence-based evidence”. evoked exaggerated. examined example, example: except excess excessive excluded excluded, exclusion excretion existing exists expand expectations experi-mental experienced experiencing experiment expert experts explain explained explanation extended external extraction extraction. extraneous facilitate fact factors failure failure, far field final finding findings findings, findings. fine firm five flow flowchart focus focused follow-up follow-up). follow-up. follow-up; followed followed-up following for form form. forms found four framework framework. frameworks frequently from from, frontal full full-text full-text). full-text. function functional further future gather gave gender, go goes great), greater group group. groups groups, groups. group’ guarantee guaranteed guess guide guidelines had haematoma half harm harm. harmful harms has have health heart helps heterogeneity high high-quality higher highest highlights highly history homeostasis, hospital, hot however, human humans hypertens* hypertension hypertension). hypertension, hypertension-related hypertension. hypertension: hypertension’ hypertensive hypertensive) hypertensive. hypotensive hypothalamus hypothyroidism ideal ideas, identification identified identified. identify idiopathic if illness) illustrated impact implemented importance important important. important: impossible improve improves in in, inappropriate include included including including, inclusion inclusion. inconclusive increase increased increases increasing incredible indeed, index individual individualised induce indvidualised inert inert, inevitably infarct, influence inform information information” informing initiation inserted instantaneous instead insula: intake intake, interest interested interesting intervals intervention intervention, interventions interventions, into into, intravascular investigate investigated, investigating involve involved involves involving is is, issue? it it. items its itself. journal journals judicious” justified justifies key keywords knee: known lack language languages. large largely largest laser laser-induced last leading least leave length less-positive less-serious level levels. li, like likelihood likely limit limitation limitation, limitation. limitations limitations. limited limiter line list listed lists literature literature, literature. lobe, local long-term longitudinal loss-to-follow-up: losses lost lost, low lower lowering lowers made maintain maintaining major males manage management management, managing manual many mass may may, mean meaningless measure measured measurements mechanism medication medication, medication. medication/s medications medications) medications, medications. medications” medicine, medicine: meridian meridian, meridians meta-analyses meta-analyses: meta-analysis meta-analysis, metal methodological methodologically methodologies methodology methodology, methodology. methods might mild million minimises minor minutes minutes’ mm mmHg moderate moderately modern modern, modifiable months more mortalities mortality most moxibustion multiple must myocardial n narrative narrow natural nausea nearest necessarily necessarily, necessary need needed needle needles needling needling, neither network neurogenic nighttime no no. non-pharmacological non-probability non-representative non-specific none nor not note noted noted, noted. noteworthy novel now number nurse nurses nurses’ nurse’s nursing obesity, observations occur occurred occurred. occurs of of, older on once one one, ongoing ongoing, only only. operator operators opposite or or, oranges” order ordered. organised osteoarthritis other others our outcome outcomes outcomes? outlined outlines over over-represented, overall overview p-values p.266), p.3). p.47), p.47). p.47-54. p.56), p.842), p.9) p=0.035). p=0.041). p=0.147). p>0.68; pain pain, pain: paper parentheses; part participant participants participants, participants. participants’ participate particular particular, particularly past pathophysiology pathophysiology, pathways, patient patients patients). patients, patients. patients: patients; patients’ patient’s paucity peak peaks, peer-reviewed people people, per perhaps period period) period, periods periods, permitted persistent person personnel person’s perspective, physical physiological physiology, piece pilot piloted place placebo placebo-controlled placed places placing plus point point-of-care points policies pooled population population, population-intervention-comparator-outcome populations positive possible possible, post-intervention post-intervention, post-intervention. poster potential potentially-relevant potentials, pp. pp.716-734. practice practice, practice. practice: practiced pre- pre-determined pre-hypertension pre-hypertension: pre-hypertensive pre-hypertensive, pre-identified pre-selecting pre-treatment precise precisely prehypertension, prescribed prescription presented presents presets pressure pressure, pressure. pressure: pressure? pressure?’ pressures pressures. pressure” prevent prevention previous previously, previously. primary prior priority problem problematic problems problems, procedures process processes processes. produce produces program promising promote properly prospective protocol. protocols protocols. provide provided provided, provides providing psychogenic psychotherapy publication published purpose purposes qi qi, qualified quality quality. quantitative question question, question. question: questions race, random-ised? randomi*ed randomisation randomised randomised, randomized randomized) randomly range ranged ranging rates rather rationale rats) re-reading read read; reading readings real reason, reason/s reasonable reasons reasons, rebalancing received receiving recent recognised recommend recommend, recommendations recommended recommending recommends recorded records recruited reduce reduced reduced, reduced. reduces reducing reduction reductions reference refined, regarding regular regulation relate related relates relating relation relevant relevant, relieving remain remained remained; remaining remains removed renal renin-angiotensin-aldosterone repeatable report reported reporting reporting. representative require requires research research, research. research: respectively; responsive resting restoring result result, resulted results retrieve, retrieved retrieved. returned returning review review, review. review: review?, reviews reviews, review’s rhythm risk robust role routine safe safety safety. safety: same sample sampling scope scope, screened screening screening, search searched, searched. searched: searches searches, searching secondary section section, section. section: sections sections. seems seen selected selecting selection semi-individualised sensation separately seriously services. session session, session. sessions sessions, sessions. setting setting, settings sham sham-controlled short-term should show showed shown shows significance significant significantly significantly, similar simple simpler single site six slightly small small, so so) so, so. sodium sodium, some sound, sources specifically specified specified), specified). specified, spellings stages. standardised start state stated statement, stenosis, stiffness still strain strategies strings stroke, strongly studies studies, studies. study study, subacute subjects subsequently subsequently, success such sufficient suggest suggested suggests suitable summarise summary superficial superior supporting supportive sustainable sustainable. sustained sustained. symptoms synonyms synthesis. synthesise synthesised synthesised. synthesize system system, systematic systematically systolic take taken taking term term. terms terms. test tested testing than that that's the their them then therapeutic therapy therapy, therapy: there thereby therefore therefore, these thesis they third thirty-two thirty-two, this those though three through throughout thus, time time. times title to to, today too took tool topic topic, topic. topics total traditional trained training translated translation, translation. travels treated treating treatment treatment, treatment. treatment? treatments treatments. trial trial, trial? trialed trials trials, trials. trials: true truncated trustworthy tubes tubes, twice two type type. types typically unable unavoidable unaware uncertain unchanged unclear unclear, under undergo underlying understand understood undertaken undertaken, undertaken. undetermined undetermined, unique unlikely unwell, up up. upper urgencies” use use, used used. using usually validity value variability variable variable, variable: variables variety various vasculature vasodilation, versus veterinary view vol. volume volume, vs. warm was water way” we weaned week week) week), week). weeks weeks, weeks. weight well-developed wellbeing were when when, where whether which while whilst who who, why will willing with within without word words work world's worst, worth would writers writing years years) your yourself £1 – ‘Blinding’ ‘Confounding’ ‘Essential ‘Hypertension’ ‘In ‘White’, ‘acceptable’ ‘back-chaining’, ‘blind’ ‘control ‘control’ ‘control’) ‘intervention ‘intervention’) ‘lifestyle’ ‘limiters’ ‘normal’ ‘significant’ ‘themes’, ‘treatment-as-usual’ “a “always “blood “comparison “conscientious “hypertensive “hypertentive “inappropriate” “major “powerful “significant ≥10mmHg ≥120 ≥120mmHg ≥140/90 ≥140mmHg ≥140mmHg, ≥89 ≥89mmHg ≥90mmHg

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